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Guided by Experts

Online Hormone Replacement Therapy for Women

A mature woman sits on a couch smiling in a yellow sweater, showing the success of her online hormone replacement therapy.

Is hormone imbalance stealing your joy?

You don’t have to suffer from hormone deficiency symptoms in silence. Defy Medical offers expertly guided online Hormone Replacement Therapy. This treatment utilizes bioidentical hormones to replenishes levels, so you can get back to enjoying life.

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Online Hormone Replacement Therapy patients report positive outcomes like:

  • A renewed passion for life
  • Healthy sex drive
  • Better moods
  • Relief from hot flashes and night sweats
  • Improved body composition and an easier time reaching fat loss goals
  • Less hormone-related anxiety and depression
  • Decreased pain and/or discomfort during intercourse

"I thought menopause was the only reason for hormone imbalance."

Menopause is a main cause of hormone imbalance, but there are other reasons.

These include perimenopause, certain medications and medical conditions, surgeries like a hysterectomy and/or oophorectomy, and more.

If you’re not feeling as good as you used to, it’s worth checking your levels – no matter your age.

Are you a candidate for online Hormone Replacement Therapy?

Take our 3-minute quiz to see if you’re a potential candidate for hormone therapy.

Take the Quiz

Most women need multiple hormones to feel their best.

Symptoms and comprehensive blood testing help our providers determine which hormones you require.

Estrogen supports sexual and reproductive health. Online Hormone Replacement Therapy typically includes one of two forms: Estradiol or Estriol.

This hormone is responsible for regulating ovulation and menstruation and is often an essential part of a BHRT protocol.

While it’s considered a male hormone, women need Testosterone too! It supports sexual health, desire, and more.

This androgen is key to the creation of other hormones, including Estrogen and Testosterone.

Pregnenolone is a precursor hormone to Estrogen, Progesterone, Testosterone, and Cortisol.

HRT Treatment Options

Defy Medical creates an individualized plan based on your goals, comfort level, and blood test results. There are many options available to you depending on your needs.

  • Injectable BHRT

    Hormone injections allow for careful control and quick adjustment of hormone levels.

  • Topical BHRT

    Hormones can be absorbed through the skin using topical lotions and gels.

  • BHRT Capsules

    These oral capsules deliver hormones in pill form.

  • BHRT Pellet Therapy

    Pellets are implanted under the skin to deliver a steady dose of hormones over time.

  • BHRT Suppositories

    Vaginal suppositories often help with vaginal dryness and discomfort.

“Very informative and relevant.”

Visited on March 14, 2025

Very informative and relevant.

–STEVEN TIRRE

5 out of 5

“Highly Recommend Dr. Calkins”

Visited on March 13, 2025

My quality of life has improved immensely. I highly recommend Dr. Calkins. His consultations are always collaborative—he listens carefully and provides comprehensive answers to every question.

–JL Houston

5 out of 5

“Well,my appointment with Dr.Saya was…”

Visited on March 14, 2025

Well,my appointment with Dr.Saya was very good. Happy with that, Rene the receptionist very nice and friendly, but the Nurses or Medical assistants I get the impression that they don’t want to be bothered or they are just tired and therefor sometimes they are Not so helpful.

–ANA

4 out of 5

“Ben Walker is top notch in experience”

Visited on March 15, 2025

Ben Walker is top notch in experience, strategy and communication skills within the preventative health and wellness industry.

–GREGORY WRIGHT

5 out of 5

“Excellent Appointment”

Visited on March 13, 2025

She listened to what I had to say and her recommendations were inline with my research.

–of Winnie

5 out of 5

“Very personal attention”

Visited on March 15, 2025

Very personal attention. Marissa was intelligent, thorough and interested in what I needed to talk about. How refreshing. 100% recommend.

–SHANNON STAUDT

5 out of 5

“Jill is great and always knows her…”

Visited on March 9, 2025

Jill is great and always knows her stuff.

–Daniel Cashman

5 out of 5

“Top quality care with kind…”

Visited on March 13, 2025

Top quality care with kind professionals helping every step of the way. PA J. does a great job!

–customer

5 out of 5

“Comprehensive & Compassionate Care”

Visited on March 12, 2025

Janelle is always prompt and listens. She is happy to answer questions and I never feel rushed. I am so glad I have her on my care team.

–Sara N.

5 out of 5

“Janel was great”

Visited on March 14, 2025

Janel was great. Took her time when explaining everything. Very thorough. Answered all of my questions. Knowledgeable. I’m upbeat about connecting with her at my next appointment !

–Robert S

5 out of 5

Showing our most recent 4- & 5-star reviews.

TrustScore 5 out of 5 See All 3177 Reviews on Trustpilot

No more struggling to find a provider who listens and provides solutions.

Defy Medical: Your Women’s Health Experts

For more than a decade, Defy Medical has offered Bioidentical Hormone Replacement Therapy online. Led by Medical Director Dr. Justin Saya, our experienced care team has guided thousands of patients to living happier, healthier lives – and we’re ready to help you.

With Defy Medical, you access:

Expert Care

Our providers specialize in Women’s Health and use the latest advancements in BHRT.

Convenient Telemedicine

Access virtual consultations and simple online ordering of medications.

No Subscriptions or Contracts

You control your schedule and cost decisions, and only pay for what you need.

Extended 1-Hour Consults

You can ask questions, discuss your most pressing symptoms, and be heard by your provider.

Individualized Care Plans

We go deeper to get to the root causes and create a protocol as unique as you are.

Regular Follow-Up for Optimization

We don’t leave you on your own. Tracking your progress is key to optimizing hormone levels over time.

Simple Pharmacy Ordering

Conveniently order prescriptions, supplements, and supplies through our online patient portal for direct-to-door delivery.

A Variety of Health Services

We also offer sexual health treatments, injectable nutrition, Primary Care, and more.

More Services

You May Also Be Interested In:

Menopause Treatment

Menopause and perimenopause cause many changes to the body. You may experience shifts in your skin, hair, body composition, mood, libido, and more. Address the effects of menopause to feel better.

Learn More About Menopause Treatment

Female Sexual Dysfunction

Address Female Sexual Dysfunction (FSD) with therapies designed to improve libido, enhance sensation, and ease pain during intimacy.

Learn More About Female Sexual Dysfunction