Find the root cause of your symptoms with Defy Medical.
"Why do I feel this way?"
Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.
Feel better. Defy expectations.
Defy Medical
The World’s Leading Hormone Replacement Clinic
Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.
Get Started
Wondering if HRT is right for you?
Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.
This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.
Take the Quiz
Some of Our
Core Services
For Men
Testosterone Replacement Therapy
Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).
Erectile Dysfunction
Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.
For Women
Hormone Therapy
Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).
Sexual Dysfunction
Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.
Meet our Care Team
Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.
See Our ProvidersWhat Our Patients are Saying
Showing our most recent 4- & 5-star reviews.
See All 3179 Reviews on
“Jill is great and always knows her…”
Visited on March 9, 2025
Jill is great and always knows her stuff.
–Daniel Cashman
“Ben is a personable and professional…”
Visited on March 14, 2025
Ben is a personable and professional practitioner. Great experience ⭐️🇺🇸
–Rand Eberhard
“Excellent Appointment”
Visited on March 13, 2025
She listened to what I had to say and her recommendations were inline with my research.
–of Winnie
“Very personal attention”
Visited on March 15, 2025
Very personal attention. Marissa was intelligent, thorough and interested in what I needed to talk about. How refreshing. 100% recommend.
–SHANNON STAUDT
“Three month review”
Visited on March 15, 2025
Once again, Krista was very informative and left me with no unanswered question.
–MARK WATERMEIER
“Highly Recommend Dr. Calkins”
Visited on March 13, 2025
My quality of life has improved immensely. I highly recommend Dr. Calkins. His consultations are always collaborative—he listens carefully and provides comprehensive answers to every question.
–JL Houston
“Well,my appointment with Dr.Saya was…”
Visited on March 14, 2025
Well,my appointment with Dr.Saya was very good. Happy with that, Rene the receptionist very nice and friendly, but the Nurses or Medical assistants I get the impression that they don’t want to be bothered or they are just tired and therefor sometimes they are Not so helpful.
–ANA
“Ben Walker is top notch in experience”
Visited on March 15, 2025
Ben Walker is top notch in experience, strategy and communication skills within the preventative health and wellness industry.
–GREGORY WRIGHT
“Janel was great”
Visited on March 14, 2025
Janel was great. Took her time when explaining everything. Very thorough. Answered all of my questions. Knowledgeable. I’m upbeat about connecting with her at my next appointment !
–Robert S
“Very informative and relevant.”
Visited on March 14, 2025
Very informative and relevant.
–STEVEN TIRRE
News and Health Articles
Learn more about integrative therapies, hormone restoration, and more.
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Liraglutide is a GLP-1 agonist that can help with blood sugar management and weight loss. Learn more about how Liraglutide works.
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Are GLP-1 Agonists the Secret to Weight Loss?
GLP-1 agonists like Semaglutide impact blood sugar and support metabolic health. Recently, they've shown promise in helping with weight loss.
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