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Find the root cause of your symptoms with Defy Medical.

"Why do I feel this way?"

Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.

Feel better. Defy expectations.

Defy Medical

The World’s Leading Hormone Replacement Clinic

Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.

Get Started

Wondering if HRT is right for you?

Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.

This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.

Take the Quiz

Some of Our

Core Services

For Men

Testosterone Replacement Therapy

Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).

Learn More About Testosterone Replacement Therapy

Erectile Dysfunction

Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.

Learn More About Erectile Dysfunction

For Women

Hormone Therapy

Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).

Learn More About Hormone Therapy

Sexual Dysfunction

Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.

Learn More About Sexual Dysfunction

Meet our Care Team

Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.

See Our Providers

What Our Patients are Saying

Showing our most recent 4- & 5-star reviews.

TrustScore 5 out of 5 See All 3180 Reviews on Trustpilot

Read More Patient Stories

“Ben Walker is top notch in experience”

Visited on March 15, 2025

Ben Walker is top notch in experience, strategy and communication skills within the preventative health and wellness industry.

–GREGORY WRIGHT

5 out of 5

“And informative and caring practitioner…”

Visited on March 13, 2025

Kristian was very thorough and informative as we discussed my recent lab work and medication protocol. Her explanations were enlightening and I did not feel rushed whatsoever. I am so grateful for the time spent with a caring practitioner!

–Colleen Fendley

5 out of 5

“Excellent Appointment”

Visited on March 13, 2025

She listened to what I had to say and her recommendations were inline with my research.

–of Winnie

5 out of 5

“Very personal attention”

Visited on March 15, 2025

Very personal attention. Marissa was intelligent, thorough and interested in what I needed to talk about. How refreshing. 100% recommend.

–SHANNON STAUDT

5 out of 5

“Jill is great and always knows her…”

Visited on March 9, 2025

Jill is great and always knows her stuff.

–Daniel Cashman

5 out of 5

“Ben is a personable and professional…”

Visited on March 14, 2025

Ben is a personable and professional practitioner. Great experience ⭐️🇺🇸

–Rand Eberhard

5 out of 5

“Three month review”

Visited on March 15, 2025

Once again, Krista was very informative and left me with no unanswered question.

–MARK WATERMEIER

5 out of 5

“Very informative and relevant.”

Visited on March 14, 2025

Very informative and relevant.

–STEVEN TIRRE

5 out of 5

“Highly Recommend Dr. Calkins”

Visited on March 13, 2025

My quality of life has improved immensely. I highly recommend Dr. Calkins. His consultations are always collaborative—he listens carefully and provides comprehensive answers to every question.

–JL Houston

5 out of 5

“Well,my appointment with Dr.Saya was…”

Visited on March 14, 2025

Well,my appointment with Dr.Saya was very good. Happy with that, Rene the receptionist very nice and friendly, but the Nurses or Medical assistants I get the impression that they don’t want to be bothered or they are just tired and therefor sometimes they are Not so helpful.

–ANA

4 out of 5