First, wash your hands with soap and water

How to Apply: Progesterone cream should be applied once per day in the evening unless otherwise instructed by your physician. Anytime up until the hour of bedtime is a good time to apply progesterone.

Where to Apply: Progesterone may be applied to upper/inner arms, shoulders, upper pectoral areas, inner thighs, neck, or abdomen.

**Please note: These instructions apply only to progesterone cream only. If your Progesterone cream also contains ‘Bi-Est’ or estrogen, do not apply to upper pectorals, chest, or neck. See Bi-Est instructions. Contact our office if you are not sure what your hormone cream contains.

Always Remember

  • Limit your contact with other people or animals for 30min after applying progesterone cream. It is possible to transfer transdermal hormones to others if it is not fully absorbed.
  • Wash hands immediately after applying progesterone cream
  • Do not mix or layer over other hormone creams or skin lotions
  • Do not bathe or shower for 40min after applying cream
  • Do not exercise or promote sweating for 2 hours after application
  • Always be sure to follow the directions provided by your pharmacy and physician.
Please contact our medical office if you have any questions.