What Does Ketamine Do?

Ketamine has been used for decades as an anesthetic during surgery and other procedures. It’s also shown promise as a powerful treatment for certain mental disorders.

The medication works by blocking N-methyl-D-aspartate (NMDA) receptors in the brain. These receptors play a crucial role in pain perception and signal transmission.

Blocking NMDA receptors disrupts communication between neurons, reducing pain signals and creating a feeling of detachment that is often described as “floating.” At higher doses, Ketamine causes unconsciousness, which is what makes it suitable as an anesthetic.

Ketamine interacts with other receptors like AMPA, as well, and this potentially contributes to its pain-relieving and sedative effects.

Emerging research shows that Ketamine can help with synaptogenesis, or the creation of new synapses within the brain. Ketamine has demonstrated success in treating conditions like treatment-resistant depression, anxiety, PTSD, and other mental health disorders.

Anecdotally, many patients report relief from debilitating mental illness symptoms after receiving supervised low-dose Ketamine IV therapy.

What is Ketamine Therapy?

Ketamine therapy utilizes Ketamine’s ability to rewire the brain to treat conditions like:

• Treatment-resistant depression
• Post-traumatic stress disorder (PTSD)
• Anxiety disorders
• Chronic pain
• Improving brain function to address issues like brain fog and forgetfulness

In this therapy, Ketamine is administered intravenously at a lower dose to avoid unconsciousness. Patients often describe feeling deeply relaxed with free-flowing thoughts. Once administered, Ketamine begins taking effect on the brain.

Many patients report an immediate improvement in their symptoms, while others see benefit after several sessions.

What is a Ketamine IV Treatment Like?

At Defy Medical, we administer Ketamine in a comfortable and calming environment.

The medication will be delivered intravenously over a period of 40-60 minutes. Throughout the session, a qualified healthcare professional will be present to monitor your well-being and address any concerns.

Defy Medical provides amenities like an eye mask, reclining chair, and headphones that play relaxing music.

Many patients report feeling a sense of calm and detachment during their IV session. You may imagine pleasant visualizations like a beach or a jungle. Typically, patients find the experience to be enjoyable.

Some patients don’t feel as much of an effect during their session, but Ketamine impacts synaptic connections regardless.

Who is Not a Good Candidate for Ketamine Therapy?

While Ketamine treatment is generally considered safe, certain pre-existing conditions may make it unsuitable for some patients.

Here are situations where Ketamine therapy might not be recommended:

• Heart or cardiovascular conditions: Ketamine can raise blood pressure and heart rate, potentially posing risks for those with pre-existing issues.
• High blood pressure: While some with hypertension may be considered on a case-by-case basis, careful monitoring is essential.
• Liver disease: Ketamine metabolism depends on the liver, so existing liver problems could be a contraindication.
• Substance abuse disorders: Addiction history requires caution due to potential for misuse or psychological dependence.
• Benzodiazepine dependence: Long-term use can reduce Ketamine’s effectiveness. In some cases, adjusting medication may be necessary. Keep in mind that you should never change your medication regimen without guidance from a medical provider.
• Certain psychotic disorders: Ketamine, in rare cases, may worsen pre-existing psychosis.
• Pregnancy and breastfeeding: Not advised due to safety concerns for mother and baby.

We recommend consulting with a qualified healthcare professional to discuss your specific situation and determine if Ketamine therapy is right for you.