Skip to content
A man smiles while looking toward the camera

Trimix helps men with severe dysfunction regain their sexual performance.

Trimix is a combination of alprostadil, papaverine, and phentolamine, administered via penile injection.

This potent blend dilates the blood vessels to improve blood circulation, resulting in powerful erections in as little as 20 minutes. Trimix is stronger than standard erectile dysfunction prescriptions and is often prescribed when other medications fail to bring results.

If you’re considering Trimix, you may be wondering how much it costs. We’ll go into detail about this ED therapy and provide a cost estimate.

Factors that Impact Trimix Cost

There are many elements that affect the cost of Trimix.

Your dosage will dictate how many injections come within your vial, which will impact the cost.

A typical Trimix protocol is a dosage between .05mL and 0.12mL. Most patients who have not tried Trimix before will start at the lowest dosage to ensure safe use.

The next factor that determines Trimix cost is the vial size and strength you’re prescribed. Defy Medical offers access to a 5mL bottle, which typically lasts patients two to three months depending on their dosage.

Another factor that impacts cost is how often you inject. You can inject Trimix up to three times a week, waiting 24 hours between each injection.

Your activity level will determine how much you wish to inject within those parameters, which will dictate how often you need to purchase new vials.

So, How Much Does Trimix Cost?

On average, Trimix costs between $1.39 and $3.30 per injection, calculated from the smallest dosage to the largest.

This equals to approximately 100 injections per vial at the .05 mL dosage, and 42 injections per vial for the 0.12 mL dosage. For most patients, a vial lasts them two to three months.

*This is a cost estimate based on standard dosages. Your cost may be more or less depending on your protocol. This figure is meant for illustrative purposes and is not a price guarantee. This cost estimate is for Trimix medication and does not include consultation, shipping, or injection and disposal supplies. If you have more questions about the cost of Trimix, connect with a Patient Advocate today.

Other Costs to Consider

There are other costs to consider in addition to medication. Because Trimix is an intensive therapy, Defy Medical offers in-depth consultations to give proper instructions and address any questions or concerns.

The cost of an initial Trimix consultation with an experienced Defy Medical provider is $99.

Shipping and injection supplies also affect the overall cost. Typically, Trimix can be shipped with standard shipping because it is lyophilized and does not require ice.

Injection medication requires supplies, as well. These include syringes, alcohol wipes, and sharps containers for safe disposal. Defy Medical offers access to these supplies at affordable prices.

Different Types of Trimix

The above estimate is calculated based on the price of Trimix and Super Trimix, but your cost will vary depending on which potent formula you utilize. These include:

  • Trimix: The original formula, Trimix includes Alprostadil, Papaverine, and Phentolamine.
  • Super Trimix: Similar to Trimix but contains Phentolamine at a doubled dosage.
  • Bimix: Includes Papaverine and Phentolamine but excludes Alprostadil for those sensitive to it.
  • Super Bimix: Offers Phentolamine at a dosage twice as high as that of Bimix.
  • Quadmix: Consists of Papaverine, Phentolamine Mesylate, Prostaglandin, and Atropine Sulfate.
  • Super Quadmix: Contains Phentolamine at twice the dosage found in Quadmix.

We typically recommend patients start with the basic Trimix formula unless they have a known sensitivity or allergy to Alprostadil (in which case, Bimix would be more appropriate).

If for some reason Trimix doesn’t bring results, patients can try other formulas like Super Trimix and Quadmix.

Cost of Other ED Medications

If you’re interested in other ED solutions besides Trimix, Defy Medical offers access to industry-leading prices on oral prescriptions.

Sildenafil and Tadalafil are vasodilators used in many ED medications. Vasodilators expand the blood vessels to improve blood flow to the penis, leading to successful erections in most men.

You may know these medications by their brand names, Viagra and Cialis, respectively.

Cost of Sildenafil with Defy Medical*:

  • 17mg: $1.50 per tablet
  • 36mg: $2.50 per tablet
  • 60mg: $3.00 per tablet
  • 80mg: $3.00 per tablet
  • 115mg: $4.50 per tablet

Cost of Tadalafil with Defy Medical*:

  • 3mg: $1.50 per tablet
  • 7mg: $2.50 per tablet
  • 12mg: $3.50 per tablet
  • 5mg: $5.00 per tablet

Defy Medical also offers other medications and combination therapies to help treat ED:

  • Vardenafil
  • Oxytocin
  • Bremelanotide
  • Topical creams
  • Sildenafil/Tadalafil
  • Bremelanotide/Oxytocin/Tadalafil
  • Sildenafil/Testosterone (for TRT patients only)
  • Tadalafil/Testosterone (for TRT patients only)

*These prices do not include taxes and shipping costs.

How Common is Erectile Dysfunction?

Around 10% of all men experience erectile dysfunction (ED), and the likelihood increases with age. That’s because hormone production decreases as men get older, often leading to ED.

Symptoms of ED include:

  • Loss of rigidity
  • Unreliable penetration
  • Premature rapid ejaculation
  • Difficulties achieving orgasm
  • Delayed ejaculation

You may have one, some, or all of these symptoms if you’re experiencing erectile dysfunction.

There are also different levels of erectile dysfunction. The severity of your ED can be determined by investigating different types of function: erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction.

The International Index of Erectile Function (IIEF) questionnaire dives into these categories with in-depth questions related to sexual performance. This diagnostic tool can help identify whether your erectile dysfunction is mild to moderate or severe.

It can also identify whether other therapies may be necessary to address various issues, like Testosterone Replacement Therapy for low libido (additional blood testing and consultations are required to determine if you’re a candidate for TRT).

The Cost of Trimix with Defy Medical

Defy Medical offers access to affordable Trimix via telemedicine for qualifying patients. We also offer a wide range of other ED therapies to help regain function, improve intimacy, and boost libido.

* denotes a required field.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.