Find the root cause of your symptoms with Defy Medical.
"Why do I feel this way?"
Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.
Feel better. Defy expectations.
Defy Medical
The World’s Leading Hormone Replacement Clinic
Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.
Get Started
Wondering if HRT is right for you?
Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.
This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.
Take the Quiz
Some of Our
Core Services
For Men
Testosterone Replacement Therapy
Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).
Erectile Dysfunction
Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.
For Women
Hormone Therapy
Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).
Sexual Dysfunction
Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.
Meet our Care Team
Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.
See Our ProvidersWhat Our Patients are Saying
Showing our most recent 4- & 5-star reviews.
See All 4113 Reviews on
“Marissa was a great provider”
Visited on September 3, 2026
Marissa was a great provider, I’ve worked with different ones and she has been my favorite. She listens carefully and was very knowledgeable for my situation.
–HERNANDEZ,NICHOLE
“This is my third consult with Dr”
Visited on September 2, 2026
This is my third consult with Dr. Caulkins. It had been rescheduled and I had been distracted right at the call in time. He called and didn’t miss a beat. All went well and we discussed revised treatment options and some peptides to aid my healing from a recent injury. Make sure your support system pushes out the treatment notes.
–customer
“Very compassionate”
Visited on September 3, 2026
Very compassionate, knowledgeable and informative.
–Monica
“Great feedback”
Visited on September 2, 2026
Ben listened to my concerns and was emphatic about it. Made many suggestions and detailed explanations.
–Cliff
“Extremely informative and in depth…”
Visited on September 3, 2026
Extremely informative and in depth review of records.
–James
“She was able to answer questions no one…”
Visited on September 3, 2026
She was able to answer questions no one else had been able to answer.
Super nice!!
–FIGUEROA,LINDSAY
“Smart and friendly”
Visited on September 5, 2026
Prompt. Explained the process clearly.
–WEISENBURGER,GEORGE
“Very thorough and informative.”
Visited on September 3, 2026
Very thorough and informative.
–TUMULURI,SRINIVAS
“Beth is always patient with me and all…”
Visited on September 5, 2026
Beth is always patient with me and all my questions. Everything is explained to me clearly and any further questions I have are answered at any time. Defy has been very helpful.
–Ben
“She is a great provider”
Visited on September 5, 2026
She is a great provider
–SUZANNE MITTON
News and Health Articles
Learn more about integrative therapies, hormone restoration, and more.
See More Articles
FDA to Remove Outdated Warnings on BHRT Medications
The FDA announced that it will remove black box warnings from BHRT estrogen products. These warnings are based on outdated research.
Learn More About FDA to Remove Outdated Warnings on BHRT Medications
What is Liraglutide?
Liraglutide is a GLP-1 agonist that can help with blood sugar management and weight loss. Learn more about how Liraglutide works.
Learn More About What is Liraglutide?
Are GLP-1 Agonists the Secret to Weight Loss?
GLP-1 agonists like Semaglutide impact blood sugar and support metabolic health. Recently, they've shown promise in helping with weight loss.
Learn More About Are GLP-1 Agonists the Secret to Weight Loss?