Find the root cause of your symptoms with Defy Medical.
"Why do I feel this way?"
Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.
Feel better. Defy expectations.
Defy Medical
The World’s Leading Hormone Replacement Clinic
Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.
Get Started
Wondering if HRT is right for you?
Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.
This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.
Take the Quiz
Some of Our
Core Services
For Men
Testosterone Replacement Therapy
Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).
Erectile Dysfunction
Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.
For Women
Hormone Therapy
Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).
Sexual Dysfunction
Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.
Meet our Care Team
Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.
See Our ProvidersWhat Our Patients are Saying
Showing our most recent 4- & 5-star reviews.
See All 2786 Reviews on
“Jill always listens to you”
Visited on November 9, 2024
Jill always listens to you. She doesn’t just look at labs and give cookie cutter doses She asks how you feel and if there are any residual symptoms that you may be experiencing. My protocol is dialed in and that is in large part thanks to Jill!!!
–KATHARINE ISLER
“As always with Defy …”
Visited on November 20, 2024
As always with Defy, my consult went great. All my questions were answered and any areas for concern on my blood work were discussed. 5 stars, would do again
–JC
“Thank You!”
Visited on November 18, 2024
I really appreciate Defy and the service they provide, it’s been a huge blessing.
–Happy Coloradoan
“Mike is knowledgeable!”
Visited on November 15, 2024
Mike is knowledgeable and concerned for my situation. I appreciate his suggestions and eagerness to help.
–DAVID S
“She’s amazing”
Visited on November 15, 2024
She’s amazing! Listens so well and makes you feel comfortable. Best provider I’ve had to date 🙂
–Gabrielle B
“Ben is the best HRT provider I have…”
Visited on November 18, 2024
Ben is the best HRT provider I have ever had.
–Lucas Atwood
“Mike is always very nice to talk to and…”
Visited on November 17, 2024
Mike is always very nice to talk to and very informative. The entire experience with Defy is always good.
–JASON HUGHES
“Beth exceeded expectations”
Visited on November 17, 2024
Beth was patient, empathetic and competent. other than Dr. Saya, she did an amazing job!
–SYED MIRZADA
“Call With Dr. Caulkin”
Visited on November 15, 2024
I always speak to Dr. Saya but his appointments were way out. Dr. Culkin was great to deal with and it was good to get a different perspective. Highly recommend!
–Steve
“Mike is the Man!”
Visited on November 19, 2024
I love the way Mike can look at my blood work and literally describe the way I’ve been feeling and give advice and when necessary medication to help, I feel very confident in my care I receive here!
Mike is awesome!
–Robby M. Hoch
News and Health Articles
Learn more about integrative therapies, hormone restoration, and more.
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Liraglutide is a GLP-1 agonist that can help with blood sugar management and weight loss. Learn more about how Liraglutide works.
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Semaglutide is rising in popularity as a prescription weight loss tool. But what happens when you stop taking semaglutide?
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Are GLP-1 Agonists the Secret to Weight Loss?
GLP-1 agonists like Semaglutide impact blood sugar and support metabolic health. Recently, they've shown promise in helping with weight loss.
Learn More About Are GLP-1 Agonists the Secret to Weight Loss?