Skip to content
New Year, New You! Take 10% off Select Services for a Limited TIme. Learn more
A man and a woman sit on the couch looking at a laptop together.

Find the root cause of your symptoms with Defy Medical.

"Why do I feel this way?"

Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.

Feel better. Defy expectations.

Defy Medical

The World’s Leading Hormone Replacement Clinic

Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.

Get Started

Wondering if HRT is right for you?

Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.

This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.

Take the Quiz

Some of Our

Core Services

For Men

Learn More

Testosterone Replacement Therapy

Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).

Learn More
Learn More

Erectile Dysfunction

Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.

Learn More

For Women

Learn More

Hormone Therapy

Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).

Learn More
Learn More

Sexual Dysfunction

Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.

Learn More

Meet our Care Team

Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.

See Our Providers

What Our Patients are Saying

Showing our most recent 4- & 5-star reviews.

TrustScore 5 out of 5 See All 2929 Reviews on Trustpilot

Read More Patient Stories

“Defy Medical (Patents are treated with kindness and top notch care)”

Visited on January 5, 2025

Defy Medical, is a fantastic provider. They pride themselves with caring and pleasant patent service. I highly recommend Defy Medical. I have been a patient for many years and they have treated me like family from the start. Thank you Defy!

–FRANCIS MILLS

5 out of 5

“I appreciate the timeliness and ease of…”

Visited on January 4, 2025

I appreciate the timeliness and ease of speaking with my Doctor.

–TRUETT HARDIN

5 out of 5

“I rated my experience based off my call…”

Visited on January 5, 2025

I rated my experience based off my call but what I was not pleased with was getting this consultation set up. I was called and told that I would be connected with someone in the next 10 minutes; only to have then been told that I would need to reschedule for the next day. I am glad I did speak with Marisa who was not the original person I was set up with but, this isn’t the 1st time I’ve been rescheduled. Both occasions happen because of something on Defy’s end creating an inconvenience for me.

–Andrew

5 out of 5

“Very informative”

Visited on January 4, 2025

She had great feedback concerning my questions and made helpful suggestions.

–WESLEY DONAHUE

5 out of 5

“Professional and timely response”

Visited on January 1, 2025

Professional and timely response. The clinician was knowledgeable and handled the entire process smoothly.

–MARK WHEELER

5 out of 5

“Always polite and professional”

Visited on January 2, 2025

Always polite and professional

–DAVE KOVAR

5 out of 5

“🌟🌟🌟🌟🌟”

Visited on January 2, 2025

Jill was easy to talk to and very helpful an and informative.

–Unhappy excustomer

5 out of 5

“Dr Calkins was great”

Visited on January 2, 2025

Dr Calkins was great. He answered my questions, discussed in detail my lab results. Defined my plan for the next 6 months. Time ran out before I could think of another question.

–Patrick H

5 out of 5

“Dr Calkins and Defy Medical are great!”

Visited on January 2, 2025

Dr. Calkins is always friendly and helpful. He listens to you and offers solutions based on your bloodwork and symptoms. Defy medical has drastically improved my quality of life.

–CHRISTOPHER HAYES

5 out of 5

“I liked Marissa and thought she was…”

Visited on January 4, 2025

I liked Marissa and thought she was thorough. I particularly liked that she looked at some of my blood work that was out of balance and said, let’s do another blood test to see if we can get to the bottom of why this is always off. That gave me confidence that she was curious and looking under more rocks than other care I have had.,

–margaret ryding

5 out of 5