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Find the root cause of your symptoms with Defy Medical.

"Why do I feel this way?"

Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.

Feel better. Defy expectations.

Defy Medical

The World’s Leading Hormone Replacement Clinic

Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.

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Wondering if HRT is right for you?

Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.

This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.

Take the Quiz

Some of Our

Core Services

For Men

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Testosterone Replacement Therapy

Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).

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Erectile Dysfunction

Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.

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For Women

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Hormone Therapy

Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).

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Sexual Dysfunction

Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.

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Meet our Care Team

Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.

See Our Providers

What Our Patients are Saying

Showing our most recent 4- & 5-star reviews.

TrustScore 5 out of 5 See All 2968 Reviews on Trustpilot

Read More Patient Stories

“Dr Calkins took the time to discuss…”

Visited on January 16, 2025

Dr Calkins took the time to discuss symptoms and treatment without me feeling rushed. He agreed to my request for increased dose of one of my prescriptions so I felt listened to. Very friendly and caring.

–Dawn Anderson

5 out of 5

“Mike is Great”

Visited on January 15, 2025

Mike listened to all my concerns explained all my bloodwork & we are both on the same page with my hormone care. I’m completely pleased with him.

–Laura Kirby

5 out of 5

“Great service”

Visited on January 15, 2025

Great service, thank you very much, improved my life drastically

–B c

5 out of 5

“Always a great experience”

Visited on January 16, 2025

It’s fantastic talking to a provider who understands your needs, goals, and has you best interest in mind. I’ve worked with other clinics where I felt unheard. My experience with Defy has been wonderful and I can’t say enough about Ben. You’re in good hands with the team at Defy Medical.

–Anthony Reynolds

5 out of 5

“Good communication”

Visited on January 7, 2025

Good communication, understanding, advises accordingly, they know what they are doing.

–STEVEN P

5 out of 5

“Very insightful consult”

Visited on January 13, 2025

Very insightful consult, great information provided to ensure that all of my questions/concerns were addressed!

–ROBERT VALADEZ

5 out of 5

“Ben’s a good guy”

Visited on January 13, 2025

Ben’s a good guy. Very knowledgeable. By far the best hormone specialist I have spoke with.

–DONALD CLARK

5 out of 5

“Ben is money”

Visited on January 15, 2025

Ben was easy to talk to. Clear on everything. Was super reassuring.

–MARY H

5 out of 5

“She explained everything and was kind”

Visited on January 14, 2025

She explained everything and was kind. She seemed very knowledgeable about the care she provides.

–NANCY BURGER

5 out of 5

“Great company”

Visited on January 10, 2025

The Doctor is always well prepared, answers the questions I have and discusses any issues I have with depth and clarity. Communication is always very good whenever I have an issue. 5 stars. Zero complaints.

–MICHAEL

5 out of 5