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Find the root cause of your symptoms with Defy Medical.

"Why do I feel this way?"

Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.

Feel better. Defy expectations.

Defy Medical

The World’s Leading Hormone Replacement Clinic

Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.

Get Started
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Wondering if HRT is right for you?

Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.

This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.

Take the Quiz

Some of Our

Core Services

For Men

Learn MoreA man smiles as he runs near a bridge and body of water, showing the benefits of Testosterone Replacement Therapy online.

Testosterone Replacement Therapy

Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).

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Learn MoreA black man hugs his partner, a black woman, as they smile because they successfully treated erectile dysfunction (ED).

Erectile Dysfunction

Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.

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For Women

Learn MoreA mature woman sits on a couch smiling in a yellow sweater, showing the success of her hormone therapy.

Hormone Therapy

Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).

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Learn MoreA man and woman smile at the camera as the woman hugs the man from behind, celebrating their treatment of female sexual dysfunction.

Sexual Dysfunction

Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.

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Meet our Care Team

Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.

See Our Providers

What Our Patients are Saying

Showing our most recent 4- & 5-star reviews.

TrustScore 5 out of 5 See All 1911 Reviews on Trustpilot

Read More Patient Stories

“Extremely professional”

Visited on March 17, 2024

Extremely professional. Always makes sure I understand. Takes her time.

–KENNETH SMITH

5 out of 5

“Marisa is great!”

Visited on March 17, 2024

Marisa is great! She listens to me and each time we talk I walk away confident that my hormone levels are going to improve. This is so refreshing after trying to work with a number of local medical professionals who were not very helpful.

–Craig

5 out of 5

“Informative and nice”

Visited on March 14, 2024

Informative and nice

–BENJAMIN STANALAND

5 out of 5

“Disappointed”

Visited on March 16, 2024

Unfortunately we were not able to go forward because we had not seen a neurologist. We are pursuing an appointment now. I feel like we should have been made aware of that requirement BEFORE we did all the work, and spent all the money to get the consultation.

–SUZANNE POTTER

5 out of 5

“Beth is great!”

Visited on March 17, 2024

Beth is great. I’ve been dealing with her from the start. Easy going, simple explanation of results, and works with any new help or requests you have. Highly recommend her to anyone interested in hormone treatment.

–Kevin Thomas

5 out of 5

“It’s nice to really feel heard.”

Visited on March 16, 2024

Janel really listens to my symptoms and experiences and works with me to suggest a good plan. She has worked with a lot of menopausal women and has seen what works well.

–BECKY PHILLIPS

5 out of 5

“very good”

Visited on March 16, 2024

great consult with ben.

–DAVID HOLLE

5 out of 5

“Janell is a great listener and…”

Visited on March 16, 2024

Janell is a great listener and genuinely cares about my health. She took her time with me and thoughtfully answered my questions

–JEROME WILSON

5 out of 5

“It was great to have a doctor…”

Visited on March 14, 2024

It was great to have a doctor understand your systems and not push antidepressants. I learned a lot during my appointment about hormones and how they work. Really happy with Dr Calkins

–AMANDA MARTIN

5 out of 5

“Ben was great”

Visited on March 16, 2024

Ben was great, very helpful and knowledgeable. Made the process easy

–CHRIS C

5 out of 5